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Hoodia is a genus of 13 species in the flowering plant
family Apocynaceae, under the subfamily Asclepiadoideae.They
are stem succulents, described as "cactiform" because of their
remarkable similarity to the unrelated cactus family. They can
reach up to 1m high and have large flowers, often with tan
colour and strong smell.
Several species are grown as garden plants, and one species,
Hoodia gordonii, is being investigated for use as an appetite
suppressant.In the last few years, hoodia has been heavily
marketed for weight loss and has become immensely popular.
The use of Hoodia has long been known by
the indigenous populations of Southern Africa, who infrequently
use these plants for treating indigestion and small infections.
However, it is their centuries old use of the meat of the plant
to suppress appetite when making long hunting trips in the
Kalahari Desert that has stimulated the most interest.
In 1977, the South African Council for Scientific and
Industrial Research (CSIR) isolated the ingredient in
hoodia—now known as P57—which is responsible for its
appetite-suppressant effect, and patented it in 1996.The CSIR
then granted United Kingdom-based Phytopharm a license, and
they collaborated with the pharmaceutical company Pfizer to
isolate active ingredients from the extracts and look into
synthesizing them for use as an appetite suppressant.
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